PubMed COVID-19 Clinical Care
2491 - 2500 of 5136 results found
Applying the bioisosterism strategy to obtain lead compounds against SARS-CoV-2 cysteine proteases: An in-silico approach
Description
SARS-CoV-2 cysteine proteases are essential nonstructural proteins due to their role in the formation of the virus multiple enzyme replication-transcription complex. As a result, those functional proteins are extremely relevant targets in the
Associations of Mental Health and Experience of the COVID-19 Pandemic with United States Adults' Intentions to Be Vaccinated
Description
COVID-19 vaccine uptake in the United States has proved challenging. A deeper characterization extending beyond demographics and political ideologies of those hesitating or resisting is needed to guide ongoing conversations. This study examined
Assessment of thermal and temporal stability of SARS-CoV-2 samples using real-time qRT-PCR
Description
CONCLUSION: The SARS-CoV-2 genetic materials in commercial VTM were stable at room temperature to -80 °C for 50 days.
Antibody response in elderly vaccinated four times with an mRNA anti-COVID-19 vaccine
Description
The humoral response after the fourth dose of a mRNA vaccine against COVID-19 has not been adequately described in elderly recipients, particularly those not exposed previously to SARS-CoV-2. Serum anti-RBD IgG levels (Abbott SARS-CoV-2 IgG II Quant
An Analysis of Crisis Communication Delivered by the Chief Health Officer During the COVID-19 Pandemic in Queensland, Australia
Description
During the first year of the COVID-19 pandemic, the state of Queensland, Australia, had relative success in containing viral transmission, presenting a unique case for potential insights into effective crisis management. Limited research exists into
Active surveillance of adverse events following COVID-19 vaccines in a tertiary care hospital
Description
CONCLUSION: The study identified only 0.33% of events as serious, and 99.67% of the study population recovered from the AEFIs, which reveals that COVISHIELD™ and COVAXIN^(®) have a generally favourable safety profile. However, close monitoring is
Assessment of the early detection of anosmia-ageusia symptoms in COVID-19 on Twitter: A retrospective study
Description
CONCLUSIONS: Based on our analysis of French tweets, associations between COVID-19 and anosmia-ageusia by web users could have been found on Twitter just a few days before the official announcement but not during the early stage of the pandemic
A new fly resource to study SARS-CoV-2 infection
Description
No abstract
A cell-based assay for rapid assessment of ACE2 catalytic function
Description
Angiotensin-converting enzyme II (ACE2) is a monocarboxypeptidase expressed throughout multiple tissues and its catalysis of bioactive peptides regulates the renin-angiotensin system mediating blood pressure homeostasis. ACE2 is implicated in a
