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PubMed COVID-19 Clinical Care

1771 - 1780 of 44979 results found

Structural Relationships to Efficacy for Prazole-Derived Antivirals

Date
Wednesday, March 06, 2024 - 4:00 AM
Description
Here, an in vitro characterization of a family of prazole derivatives that covalently bind to the C73 site on Tsg101 and assay their ability to inhibit viral particle production is presented. Structurally, increased steric bulk on the 4-pyridyl of

Genomic surveillance of SARS-CoV-2 using long-range PCR primers

Date
Tuesday, March 05, 2024 - 4:00 AM
Description
INTRODUCTION: Whole Genome Sequencing (WGS) of the SARS-CoV-2 virus is crucial in the surveillance of the COVID-19 pandemic. Several primer schemes have been developed to sequence nearly all of the ~30,000 nucleotide SARS-CoV-2 genome, using a