PubMed COVID-19 Clinical Care

In this work, we present DrugSolver CavitomiX, a novel computational pipeline for drug repurposing and identifying ligands and inhibitors of target enzymes. The pipeline is based on cavity point clouds representing physico-chemical properties of the

mRNA technology has emerged as a successful vaccine platform that offered a swift response to the COVID-19 pandemic. Accumulating evidence shows that vaccine efficacy, thermostability, and other important properties, are largely impacted by intrinsic

INTRODUCTION: The COVID-19 pandemic has strained the mental and physical well-being of healthcare workers (HCW). Increased work-related stress and limited resources have increased symptoms of anxiety, depression, insomnia and post-traumatic stress

CONCLUSION: The routine use of the already established WAST-short in primary care could help identify and potentially tackle DA. Training health and social care professionals in administering the brief, non-threatening DA screening questionnaire

CONCLUSIONS AND RELEVANCE: Our study provides evidence that administering the mRNA-vaccine to pregnant females during the second trimester leads to increased levels of vaccine-specific IgA during lactation. Considering the significance of human-milk

CONCLUSION: A considerable number of Greek boys with T1DM appear to develop precocious and early puberty, raising thoughts regarding diabetes management and other possible cofactors.

No abstract

CONCLUSION: The study findings indicated the potential role of miR-223 and the dysregulation of NLRP3 inflammasome followed by IL-1β, as a regulatory factor in the pathogenesis of COVID-19, like that in other inflammatory diseases.

As the world is experiencing the pandemic of SARS-CoV-2 responsible for COVID-19, one can wonder if members of other family of viruses could possibly emerge. Can such viruses establish a worldwide distribution with consequences similar to SARS-CoV-2

SARS-CoV-2 nucleocapsid protein (N-protein) rises early in body fluids during infection and has recently been identified as a direct inducer for lung injury. However, the signal mechanism of N-protein in lung inflammatory response remains poorly