PubMed COVID-19 Clinical Care
7751 - 7760 of 44979 results found
Triggering receptor expressed on myeloid cells-1 in sepsis, and current insights into clinical studies
Description
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition receptor and plays a critical role in the immune response. TREM-1 activation leads to the production and release of proinflammatory cytokines, chemokines, as well as
Real-world effectiveness of nirmatrelvir-ritonavir versus azvudine in hospitalized patients with COVID-19 during the omicron wave in Beijing: a multicenter retrospective cohort study
Description
CONCLUSION: Among patients hospitalized with COVID-19 during the omicron wave in Beijing, similar in-hospital clinical outcomes on 28 days were observed between patients receiving nirmatrelvir-ritonavir and azvudine. However, it is worth noticing
Novel small-molecule inhibitors of SARS-CoV-2 main protease with nanomolar antiviral potency
Description
No abstract
An Incarcerated Individual With Weight Loss and Interstitial Pulmonary Infiltrates
Description
No abstract
COVID-19 vaccine refusal as unfair free-riding
Description
Contributions to COVID-19 vaccination programmes promise valuable collective goods. They can support public and individual health by creating herd immunity and taking the pressure off overwhelmed public health services; support freedom of movement by
Association between occupational stress, occupational burnout, and depressive symptoms among medical staff during COVID-19: A cross-sectional study in Chongqing, China
Description
CONCLUSION: Our results indicated that occupational stress and burnout were predictors of depressive symptoms. Occupational stress had a significant indirect effect on depressive symptoms via burnout. These results suggest that reducing occupational
Molecular Dynamics Simulations on Spike Protein Mutants Binding with Human β Defensin Type 2
Description
Human β defensin type 2 (hBD-2), a cationic cysteine-rich peptide secreted from the human innate immune system, can bind Spike-RBD at the same site as receptor ACE2, thus blocking viral entry into ACE2-expressing cells. In order to find out the
Risk of disease flares after SARS-CoV-2 mRNA vaccination in patients with systemic lupus erythematosus
Description
This study aims to elucidate the effectiveness and safety of SARS-CoV-2 mRNA vaccination in patients with systemic lupus erythematosus (SLE). We enrolled uninfected SLE patients who received two vaccine doses (BNT162b2 or mRNA-1273) and historical
Certification of stroke centers at primary hospitals and the improvement of thrombolysis n South China during 2020-2022
Description
INTRODUCTION: IVT use declined globally in 2020 due to the Corona Virus Disease 2019 (COVID-19) pandemic, but it increased in South China. This study was conducted to evaluate the association of establishing Stroke Prevention Centers (SPCs) at
