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PubMed COVID-19 Clinical Care

8411 - 8420 of 44979 results found

Safety, immunogenicity, and efficacy of a modified COVID-19 mRNA vaccine, SW-BIC-213, in healthy people aged 18 years and above: a phase 3 double-blinded, randomized, parallel controlled clinical trial in Lao PDR (Laos)

Date
Wednesday, January 03, 2024 - 4:00 AM
Description
BACKGROUND: The mRNA vaccine has demonstrated significant effectiveness in protecting against SARS-CoV-2 during the pandemic, including against severe forms of the disease caused by emerging variants. In this study, we examined safety, immunogenicity

Data-derived subtypes of delirium during critical illness

Date
Wednesday, January 03, 2024 - 4:00 AM
Description
BACKGROUND: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subtypes of

Virology-the path forward

Date
Wednesday, January 03, 2024 - 4:00 AM
Description
In the United States (US), biosafety and biosecurity oversight of research on viruses is being reappraised. Safety in virology research is paramount and oversight frameworks should be reviewed periodically. Changes should be made with care, however

Lack of association between HLA and asymptomatic SARS-CoV-2 infection

Date
Wednesday, January 03, 2024 - 4:00 AM
Description
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B*15:01 allele and asymptomatic SARS-CoV-2